No. Picaso display modules do not directly support RS232.
However, you can use MOTG-RS232 or similar modules to connect a Picaso display via RS232. This will require one of the COM ports.
When using a gen4-uLCD Picaso display, it is advisable to use gen4-MOTG-AC3. This allows easy connectivity with the MOTG-RS232 through Picaso’s COM1.

When using a non-gen4 uLCD Picaso display, a MOTG-Breadtooth can be used instead.