No. Diablo16 display modules do not directly support RS485.
However, you can use MOTG-RS485 or similar modules to connect a Diablo16 display via RS485. This will require one of the COM ports and a GPIO pin.
When using a gen4-uLCD Diablo16 display. It is advisable to use a gen4-MOTG accessory board. This allows easy connectivity with the MOTG-RS485 through Diablo16’s configurable COM port.

When using a non-gen4 uLCD Diablo16 display, a MOTG-Breadtooth can be used instead.